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The Penicillin is widely regarded as the most successful cocktail created in the 21st century — invented by bartender Sam Ross at the legendary Milk & Honey bar in New York City in 2005. Built on blended Scotch whisky with a float of peaty Islay Scotch, honey-ginger syrup, and fresh lemon juice, it's a masterclass in balance: smoky and earthy, sweet and spicy, tart and warming all at once. Named with a wink at the idea that good Scotch is medicine, it has the complexity of a decades-old classic despite being barely 20 years old. The floating Islay Scotch delivers the peaty, maritime aroma on first approach before you taste the layered body beneath — an unforgettable drinking experience.